Pesquisa | BVS Violência e Saúde

1.

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma.

Pozniak, Joanna; Pedri, Dennis; Landeloos, Ewout; Van Herck, Yannick; Antoranz, Asier; Vanwynsberghe, Lukas; Nowosad, Ada; Roda, Niccolò; Makhzami, Samira; Bervoets, Greet; Maciel, Lucas Ferreira; Pulido-Vicuña, Carlos Ariel; Pollaris, Lotte; Seurinck, Ruth; Zhao, Fang; Flem-Karlsen, Karine; Damsky, William; Chen, Limin; Karagianni, Despoina; Cinque, Sonia; Kint, Sam; Vandereyken, Katy; Rombaut, Benjamin; Voet, Thierry; Vernaillen, Frank; Annaert, Wim; Lambrechts, Diether; Boecxstaens, Veerle; Saeys, Yvan; van den Oord, Joost; Bosisio, Francesca; Karras, Panagiotis; Shain, A Hunter; Bosenberg, Marcus; Leucci, Eleonora; Paschen, Annette; Rambow, Florian; Bechter, Oliver; Marine, Jean-Christophe.

Cell ; 187(1): 166-183.e25, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38181739

2.

The genomic landscapes of individual melanocytes from human skin.

Tang, Jessica; Fewings, Eleanor; Chang, Darwin; Zeng, Hanlin; Liu, Shanshan; Jorapur, Aparna; Belote, Rachel L; McNeal, Andrew S; Tan, Tuyet M; Yeh, Iwei; Arron, Sarah T; Judson-Torres, Robert L; Bastian, Boris C; Shain, A Hunter.

Nature ; 586(7830): 600-605, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-33029006

3.

Publisher Correction: The genomic landscapes of individual melanocytes from human skin.

Tang, Jessica; Fewings, Eleanor; Chang, Darwin; Zeng, Hanlin; Liu, Shanshan; Jorapur, Aparna; Belote, Rachel L; McNeal, Andrew S; Tan, Tuyet M; Yeh, Iwei; Arron, Sarah T; Judson-Torres, Robert L; Bastian, Boris C; Shain, A Hunter.

Nature ; 590(7844): E20, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33469220

4.

Genomic profiling of combined hepatocellular-cholangiocarcinoma reveals similar genetics to hepatocellular carcinoma.

Joseph, Nancy M; Tsokos, Christos G; Umetsu, Sarah E; Shain, A Hunter; Kelley, Robin K; Onodera, Courtney; Bowman, Sarah; Talevich, Eric; Ferrell, Linda D; Kakar, Sanjay; Krings, Gregor.

J Pathol ; 248(2): 164-178, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30690729

5.

The Genetic Evolution of Melanoma from Precursor Lesions.

Shain, A Hunter; Yeh, Iwei; Kovalyshyn, Ivanka; Sriharan, Aravindhan; Talevich, Eric; Gagnon, Alexander; Dummer, Reinhard; North, Jeffrey; Pincus, Laura; Ruben, Beth; Rickaby, William; D'Arrigo, Corrado; Robson, Alistair; Bastian, Boris C.

N Engl J Med ; 373(20): 1926-36, 2015 Nov 12.

Artigo em Inglês | MEDLINE | ID: mdl-26559571

6.

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

Talevich, Eric; Shain, A Hunter; Botton, Thomas; Bastian, Boris C.

PLoS Comput Biol ; 12(4): e1004873, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-27100738

7.

NTRK3 kinase fusions in Spitz tumours.

Yeh, Iwei; Tee, Meng Kian; Botton, Thomas; Shain, A Hunter; Sparatta, Alyssa J; Gagnon, Alexander; Vemula, Swapna S; Garrido, Maria C; Nakamaru, Kenji; Isoyama, Takeshi; McCalmont, Timothy H; LeBoit, Philip E; Bastian, Boris C.

J Pathol ; 240(3): 282-290, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27477320

8.

Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.

Giacomini, Craig P; Sun, Steven; Varma, Sushama; Shain, A Hunter; Giacomini, Marilyn M; Balagtas, Jay; Sweeney, Robert T; Lai, Everett; Del Vecchio, Catherine A; Forster, Andrew D; Clarke, Nicole; Montgomery, Kelli D; Zhu, Shirley; Wong, Albert J; van de Rijn, Matt; West, Robert B; Pollack, Jonathan R.

PLoS Genet ; 9(4): e1003464, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23637631

9.

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer.

Shain, A Hunter; Giacomini, Craig P; Matsukuma, Karen; Karikari, Collins A; Bashyam, Murali D; Hidalgo, Manuel; Maitra, Anirban; Pollack, Jonathan R.

Proc Natl Acad Sci U S A ; 109(5): E252-9, 2012 Jan 31.

Artigo em Inglês | MEDLINE | ID: mdl-22233809

10.

The Genetic Evolution of Melanoma.

Shain, A Hunter; Bastian, Boris C.

N Engl J Med ; 374(10): 995-6, 2016 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-26962740

11.

A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response.

Wu, David; Hailer, Ashley A; Wang, Sijia; Yuan, Michelle; Chan, Jamie; El Kurdi, Abdullah; Han, David; Ali, Hira; D'Angio, Blaize; Mayer, Aaron; Rahim, Maha; Kondo, Ayano; Klufas, Daniel; Kim, Esther; Shain, A Hunter; Choi, Jaehyuk; Bhutani, Tina; Simpson, Gregory; Grekin, Roy C; Ricardo-Gonzalez, Roberto; Purdom, Elizabeth; North, Jeffrey P; Cheng, Jeffrey B; Cho, Raymond J.

Sci Immunol ; 9(91): eadi2848, 2024 Jan 26.

Artigo em Inglês | MEDLINE | ID: mdl-38277466

12.

Integrative genomic and functional profiling of the pancreatic cancer genome.

Shain, A Hunter; Salari, Keyan; Giacomini, Craig P; Pollack, Jonathan R.

BMC Genomics ; 14: 624, 2013 Sep 16.

Artigo em Inglês | MEDLINE | ID: mdl-24041470

13.

Melanoma Genomics: Shifting Focus from Inter- to Intrapatient Variation.

Shain, A Hunter.

Cancer Discov ; 13(6): 1294-1296, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-37264823

14.

STmut: a framework for visualizing somatic alterations in spatial transcriptomics data of cancer.

Chen, Limin; Chang, Darwin; Tandukar, Bishal; Deivendran, Delahny; Pozniak, Joanna; Cruz-Pacheco, Noel; Cho, Raymond J; Cheng, Jeffrey; Yeh, Iwei; Marine, Chris; Bastian, Boris C; Ji, Andrew L; Shain, A Hunter.

Genome Biol ; 24(1): 273, 2023 Nov 30.

Artigo em Inglês | MEDLINE | ID: mdl-38037084

15.

The genetic evolution of acral melanoma.

Wang, Meng; Fukushima, Satoshi; Sheen, Yi-Shuan; Ramelyte, Egle; Pacheco, Noel Cruz; Shi, Chenxu; Liu, Shanshan; Banik, Ishani; Aquino, Jamie D; Acosta, Martin Sangueza; Levesque, Mitchell; Dummer, Reinhard; Liau, Jau-Yu; Chu, Chia-Yu; Shain, A Hunter; Yeh, Iwei; Bastian, Boris C.

bioRxiv ; 2023 Oct 19.

Artigo em Inglês | MEDLINE | ID: mdl-37904969

16.

Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Wang, Meng; Banik, Ishani; Shain, A Hunter; Yeh, Iwei; Bastian, Boris C.

Genome Med ; 14(1): 65, 2022 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-35706047

17.

The landscape of driver mutations in cutaneous squamous cell carcinoma.

Chang, Darwin; Shain, A Hunter.

NPJ Genom Med ; 6(1): 61, 2021 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-34272401

18.

BRAF^V600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB.

McNeal, Andrew S; Belote, Rachel L; Zeng, Hanlin; Urquijo, Marcus; Barker, Kendra; Torres, Rodrigo; Curtin, Meghan; Shain, A Hunter; Andtbacka, Robert Hi; Holmen, Sheri; Lum, David H; McCalmont, Timothy H; VanBrocklin, Matt W; Grossman, Douglas; Wei, Maria L; Lang, Ursula E; Judson-Torres, Robert L.

Elife ; 102021 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-34812139

19.

UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma.

Bowman, Robert L; Hennessey, Rebecca C; Weiss, Tirzah J; Tallman, David A; Crawford, Emma R; Murphy, Brandon M; Webb, Amy; Zhang, Souhui; La Perle, Krista Md; Burd, Craig J; Levine, Ross L; Shain, A Hunter; Burd, Christin E.

Life Sci Alliance ; 4(9)2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34210801

20.

Author Correction: From melanocytes to melanomas.